GENERAL BIOLOGY AND MEDICAL GENETICS

Degree course: 
Corso di First cycle degree in Dental Hygiene
Academic year when starting the degree: 
2016/2017
Year: 
1
Academic year in which the course will be held: 
2016/2017
Course type: 
Basic compulsory subjects
Credits: 
2
Period: 
First Semester
Standard lectures hours: 
24
Detail of lecture’s hours: 
Lesson (24 hours)
Requirements: 

none

Assessment: 
Voto Finale

CHEMISTRY AND BIOCHEMISTRY Teacher dr Manuela Viola
The goal of course is to give knowledge bases that support the following and deepening learning in other areas.

BIOLOGY AND GENETICS Teacher dr Roberto Valli.
Goal of the course: to give the basis of the knowledge of general biolgy and medical genetics, foundamental subjects of other future disciplines.

Lessons programm
CHEMISTRY AND BIOCHEMISTRY Teacher Dr Manuela Viola
Atomic structure, orbital and electron configuration
isotopes, chemical bonds, Lewis theory, IUPAC and traditional nomenclature; solutions: properties and concentrations, chemical reactions, kinetics, thermodynamics, acids and bases, buffers; Carbon hybridization, sigma and pi bonds, isomerism and chirality; functional groups; aa, proteins and lipids simple and complex; carbohydrates, simple and complex, nitrogenous bases, ATP, NAD and FAD,
Metabolism of glucose, triglycerides and proteins.
Haemoglobin and myoglobin.
Bioenergetics
Lipoproteins metabolism
Cholesterol metabolism
Nitrogen metabolism
Hormone metabolism and cellular activation

GENERAL BIOLOGY AND MEDICAL GENETICS. Docente Roberto Valli
The molecules of life. The cell: Introduction, prokaryotes-eukaryotes differences. Membrane structure. The Cytoskeleton. The nucelus. The cellular organelles. Mitosis and Meiosis. Gametogeneis. Mendel’s laws. Allelism and chromosomic theory of heredity. Chromosomic determination of sex. Morgan’s experiments. Linkage theory. DNA: Structure and duplication. mRNA, tRNA, rRNA: structure and trascription. The mechanism of translation. Structure of chromosomes, classification and evolution. Genic and chromosomal mutations, biological menaing and association with pathologies in human. Heredity study of human pathologies: pedigrees for autosomal recessive, autosomal dominant and X-linked disorders. Cytogenetics techniques introduction.

Tipologia delle attività didattiche
CHEMISTRY AND BIOCHEMISTRY Docente Manuela Viola
The teaching consists in frontal lessons and in a test exam with discussion of the questions.
GENERAL BIOLOGY AND MEDICAL GENETICS: The teaching consists in frontal lessons

Assessment methods
The student must take a written test consisting of 30 multiple choice questions (4 answers with only one true) on chemical and biochemical applications, and 15 multiple choice questions (5 answers with only one true) of general biology. In the first test each question is worth 1 point and in the second 2. The tests are to be solved in 90 minutes.
The questions will be related to the program of the teachings of C.I. to define the knowledge and understanding (50%), the ability to apply knowledge and understanding (25%), communication skills (5%) and the ability to learn (20%) the relationship in chemistry, biochemistry and biology.
To pass the written examination, students must achieve a score of at least 17/30 in both tests; this will give access to the oral exam which consists in the re-discussion of mistakes made and in a couple of questions on questions relating to the program of the teachings of C.I. to define the knowledge and understanding (25%), the ability to apply knowledge and understanding (25%), communication skills (25%) and the ability to learn (25%), in relation to: the chemical molecules, to metabolism of human cells; the interactions between the metabolism in the human body; the molecular basis of heredity and formal and medical genetics.
The final mark is unique for C.I.

Testi e materiale didattico
Chimica per le scienze biomediche Sackheim G.I. Lehman D.D. Ed. EdiSes
Chimica e biochimica per le lauree triennali dell’area biomedica Samaja M. Paroni P. Ed. Piccin
Chimica, biochimica e biologia applicata
di M.Stefani, N.Taddei Zanichelli
Slide lesson on the Blackboard Learning System
Bonaldo, Duga, Pierantoni, Riva, Romanelli “Biologia e Genetica” EdiSES
SADAVA D. “Elementi di Biologia e Genetica” Zanichelli
PDF files of the lessons