CELL MODELS AND BIOMEDICAL APPLICATIONS
- Overview
- Assessment methods
- Learning objectives
- Contents
- Bibliography
- Delivery method
- Teaching methods
- Contacts/Info
In order to follow the course, adequate knowledge of cytology, molecular biolo-gy, biochemistry and physiology is required.
Oral exams. The students need to demonstrate sufficient knowledge of the topics presented during the course. They will also be evaluated for their ability to pre-sent a short production (pptx is welcome), based on the consulting of research articles that they have freely consulted and concerning a topic related to the con-tents of the course. Basic knowledge will contributes for 75% of the final score. The presentation will contributes for 25% of the final score. Minimal score is fixed at 18/30
The aim of the course is to introduce the biological and molecular aspects of staminal cells, and their derivatives, to explore how these mechanisms lead and support the study and cure some disorders. Emphasis will be given to the inher-ent potential of devices, comprised of biocompatible 3D scaffolds associated with cells and their derivatives, in regenerative medicine application.
This course will also provide the students the opportunity to grow up as learners and as effective contributors by:
1. be responsible for their own learning and for the depth of their own study
2. to take advantage of all the available resources to integrate the lecture materi-al and academic staff knowledge.
3. Working in team, in particular during the laboratory experiences
4. Developing communication skills by effective interaction with peers and aca-demic staff.
1- Lectures (36 h)
Section 1: Stem cells and regenerative medicine.
- The biology of embryonic and adult stem cells.
- Stem cells as model for in vitro and in vivo experiments to study diseases
- Stem cells and cell derivatives in regenerative medicine
- Natural and synthetic scaffold: composition, structure, characteristics and the rule of extracellular matrix
Section 2:
- regulation and law in Europe and Italy about the cell therapy
- from the bench to the bed concept
- clinical application and case presentation about cell therapy
2- Laboratory experiences (18 h)
The practical lessons consist of:
- use of a 3D printer to prepare small scaffold and prosthesis
- preparation and accomplishment of viability and proliferation assay of cells seeded on the scaffold previously prepared
- arrangement of sample for optical and SEM observation
No textbooks are available for this multidisciplinary course. The students will be provided with scientific review and research articles on the various topics dis-cussed during the course.
The course provides lectures-style instruction and laboratory experiences. Laboratory experiences are organized in order to adopt the rules to work independently, in safety and as a team.
The teacher receives the students by appointment via e-mail (rosalba.gornati@uninsubria.it