BIOCHEMISTRY
The main biomolecules of the organism: sugars, aminoacids, lipids, cholesterol, energy molecules. Reserve molecules, glycogen and triglycerides.
Oxygen transporters.
Enzymes and vitamins.
Metabolism in normal and pathological conditions.
Lipoproteins, bile acids and hints on cholesterol metabolism.
The main biomolecules of the organism: sugars, aminoacids, lipids, cholesterol, energy molecules. Reserve molecules, glycogen and triglycerides.
Proteins: peptide bond, aminoacidic sequence, three-dimensional structure (eg collagen); post-translational modifications, phosphorylations, glycosilations, proteolysis, bonds with coenzymes
Oxygen transporters: Hemoglobin / Myoglobin
Enzymes: properties, kinetics, inhibitions, regulation, specificity, nomenclature, hints of enzyme co-factors.
Vitamins.
Metabolism: anabolism and catabolism, bonds and regulations; bioenergetics: ATP- phosphorylation at the substrate level and NAD + / FAD-reducing power
Respiratory chain.
Glycolysis, glycogen metabolism and effect of insulin and glucagon.
Krebs cycle, gluconeogenesis and their regulation.
Nitrogen metabolism, transamination, transamination, urea cycle and uric acid.
Fat metabolism and metabolic adaptations in fasting.
Heme catabolism and albumins.
Lipoproteins, bile acids and hints on cholesterol metabolism.
Degradation of aminoacids and urea synthesis.
Aminoacid derivatives and nucleotide synthesis (outline)
Insulin / glucagon regulation.
Oral lessons in the classroom, including discussions regarding the biochemistry in everyday life. The presentations are then provided to the students via e-learning system.
Students that have doubts regarding the material and lessons, could ask for an appointment with the Professor, by writing an email at jenny.karousou@uninsubria.it.