Introduction to Organic Chemistry (historical notes and varieties of organic molecules). Atomic Orbitals, hybridization, ionic and covalent bonds, molecular orbitals
Electronegativity and bond polarization. Non bonding interactions, Inductive and resonance effects
Acids and bases in organic chemistry
Main functional groups, their nomenclature and reactivity
Nucleophiles and electrophiles, Carobocations and their transpositions, carbanions and radicals
Principles of organic stereochemistry (molecular symmetry, chirality, stereocentres, absolute and relative configuration descriptors)
Alkanes and cycloalkanes: structure and nomenclature. Concformational analysis of open chains
alkenes and polyenes: geometric isomerism and electrophilic addition (regioselectivity, spereospecificity and stereoselctivity)
Addition of strong and weak acids, alogens, hydroboration, oxymercuriation, oxidation. Reactivity of conjugate dienes: 1,4-addition, Diels-Alder reaction.
Alkynes
Alogenoalkanes: Nucleophilic substitution reaction (Sn1 and Sn2) and elimination (E1 and E2)
Alcohols, ethers and epoxides.
Aldehydes, ketones and their derivatives: addition of water, alcohols, cyanides, cyanides. Addition of Grignard reagents. Reactions with ammonia derivatives: imines, enamines, oxymes, hydrazones, acetals, ketals and cyanohydrins. Wittig reactions. Keto-enol tautomerisation: enols, enolates and aldol condensation.
Carboxylic acids and their derivatives: esters, acyl halides, anhydrides, nitriles, amides. Acylic nucleophilic substitution. Claisen condensation, Acetacetic and malonic synthesis. Michael addition