Pharmacokinetics. Drug absorption, bioavailability and bioequivalence, Routes of administration. Distribution of drug. Metabolism of drug, clearance, variability in drug metabolism. Excretion (renal excretions, biliary and fecal excretion, excretion by other routes). Pharmacodynamics. Mechanisms of actions of drug. Drug receptors, structure/activity relationship. Agonist and antagonist. Quantification of drug/receptor interaction, dose/response relationship, affinity, efficacy, potency, and relative efficacy. Pharmacological receptors.
Pharmacological studies. Pre-clinical and Clinical pharmacological studies.
Variability in drug response. Interactions between drugs, genetic variability, pharmacogenomics