BIOCHEMISTRY 1

Degree course: 
Corso di Long single cycle degree (6 years) in MEDICINE AND SURGERY
Academic year when starting the degree: 
2018/2019
Year: 
1
Academic year in which the course will be held: 
2018/2019
Course type: 
Basic compulsory subjects
Main course: 
Credits: 
5
Period: 
Second semester
Standard lectures hours: 
60
Detail of lecture’s hours: 
Lesson (50 hours), Exercise (10 hours)
Requirements: 

To attend the course the student should have positively passed the medical chemistry exam.

Final Examination: 
Orale

The exam of biochemistry has a single note that is obtained after passing the exam of biochemistry 2. The exam will have to be supported in two separate tests on different dates, the first will focus on the topics of biochemistry 1 and the second will focus on topics of biochemistry 2. The average of the two exams will constitute the final grade. However, in order to take the biochemical 2 exam, the student must have successfully passed the biochemical exam 1.
The exam for the biochemistry module 1 consists of a written test and an oral exam. The written test consists of 30 multiple-choice questions (five possible answers, one or more of which is true and to be identified by the student) regarding the comprehension of the topics covered. The evaluation will be insufficient if the correct answers will be less than 18. The note is not reduced by incorrect answers. The oral exam will be supported only by students who have successfully passed the written exam and will consist of questions related to the written test.

Assessment: 
Voto Finale

The course aims at providing a complete overview of the structural characteristics and functional properties of the main biomolecules of biomedical interest, to understand the alterations that may cause diseases. The approach is mainly based on the biochemistry point of view.

The properties of living matter and water.
Reserve and structure polysaccharides.
The reserve and structure lipids. Steroids: cholesterol and bile acids.
Peptides. Protein structure. Glycoproteins.
Oxygen transporters: myoglobin and hemoglobin.
Enzymes: properties and enzymatic kinetics. Regulatory enzymes. The water-soluble vitamins and the derived coenzymes.
The fat-soluble vitamins.
The structural organization of biological membranes. Mitochondrial Bioenergetic and molecular basis of mitochondrial diseases.
Main molecular metabolismo of sugars, lipids, aminoacids, and hemoglobin.

Bassi, Boffi et al.
Biochimica
Ediermes

Siliprandi, Tettamanti.
Biochimica medica.
Piccin.

Nelson, Cox.
I principi di biochimica di Lehninger.
Zanichelli.

Berg, Tymoczko, Stryer.
Biochimica.
Zanichelli.

Devlin
Biochimica con aspetti clinici
Edises

Convenzionale

The course is organized with lectures that provide for slide projections (usually in English). During the explanation in the classroom the students are invited to interact with the teachers with questions and curiosity. During the lectures the teachers will also present cases and daily facts that can make the application / importance of the subjects of the teachings understand. Students have the obligation to attend classes as established in the educational regulations of the study course and to sign the time sheet for taking the exam. Teachers undertake to make projected presentations available to lectures and other material of interest (articles) through the University computer platforms (e-learning) to which students have access.

In the teacher's presentations there will be links to web pages for further information. For reception students make an appointment by email with the teachers.
Student reception: appointment by e-mail.