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Bioinformatics

Degree course: 
Corso di First cycle degree in BIOLOGICAL SCIENCES
Academic year when starting the degree: 
2017/2018
Year: 
3
Academic year in which the course will be held: 
2019/2020
Course type: 
Compulsory subjects, characteristic of the class
Language: 
Italian
Credits: 
6
Period: 
Second semester
Standard lectures hours: 
56
Detail of lecture’s hours: 
Lesson (40 hours), Laboratory (16 hours)
Requirements: 

Solid background in genetics, biochemistry and molecular biology

Final Examination: 
Orale

Written exam only, with three open questions and four multiple-choice questions. The first two questions are very general and regard whole lectures with the aim to evaluate the ability to manage with the contents. In the third question a comment is required on one of the results obtained during practical sessions to evaluate the ability to transfer theoretical knowledge into practice.

Assessment: 
Voto Finale

Acquisition of theoretical and operative skills with reference to morphologic-functional skills
Understanding the mechanisms of structural and functional evolution of biological sequences and structures
Acquisition of specific applicative skills with reference to all-purpose practical and instrumental procedures in biological research
Methods for the analysis of biological sequences. Methods for deterministic analysis of protein structures and their application to structure prediction.
Acquisition of suitable skills to develop and further gain deeper knowledge in the topics of the course and to improve continuous education in the field
Learning modern tools for querying biological databases

Bioinformatics resources (1 ECTS). Working with sequences (2 ECTS). Working with structures (1,5 ECTS). Genomics and beyond (1,5 ECTS)

Part 1 – Bioinformatics resources
Introduction to Bioinformatics
Biological databases
Practical worksession 1
Part 2 – Working with sequences
Sequence alignment
Functional patterns and motifs
Molecular evolution
Practical worksession 2
Part 3 – Working with structures
Structural analysis of proteins
Protein structural prediction
Practical worksession 3
Part 4 – Genomics and beyond
Genomics
Post-genomics
Systems biology
Practical worksession 4

M. Helmer Citterich, F. Ferrè, G. Pavesi, C. Romualdi, G. Pesole, "Fondamenti di Bioinformatica", Zanichelli, 2018

Convenzionale

Traditional classroom lectures and practical lectures in the computer room

None

Professors

FASANO MAURO